Effect of ether anesthesia on 17-hydroxy-corticosteroid secretion in dogs.

MURA. Efect of ether anesthesia on r7-hydroxycur~icosteroid secretion in dogs. Am. J. Physiol. rg7(6): 1261-1262. rg5g.--In dogs with previously cut dorsal spinal roots (T1r-L3), adrenal venous blood was collected without anesthetic or pain. Ether was then inhaled for 30-60 minutes. During and after ether inhalation, adrenal venous blood was again collected and the plasma was analyzed for I 7-hydroxycorticosteroids (I 7-OHCS). The mean preinhalation control secretion rate of I 7-OHCS by one adrenal was o. IO (0.06-0.20) &kg/min. During ether inhalation it increased to 0.34-1.2 pg/kg/min. Thirty to sixty minutes after the end of ether inhalation the secretion rate increased to a maximum of 0.79-I .8 pg/kg/min. and then decreased.